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The interactions of protein kinases and phosphatases with their regulatory subunits and substrates underpin cellular regulation.
Osprey is a software platform for the visualization of complex biological interaction networks. Annotated interaction data maintained by the BioGRID. Osprey is developed by the TyersLab. And is a part of the BioGRID. To operate and is compatible with Windows. And supported by the National Institutes of Health. Canadian Institutes of Health Research.
The reversible phosphorylation of proteins is one of the most important post-translational modifications, which is involved in varieties of cellular processes and plays a critical role in activation, inactivation and regulation of proteins. Two types of enzymes, known as protein kinase.
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The web page had the following in the homepage, "Search for YORF names, gene Names, or external identifiers." I saw that the web site stated " Examples YAL001C, Ste20, S000000001." They also said " Dont use ambiguous identifiers if possible, because they will return multiple results. The Osprey Network Visualization System. PhosphoGRID is an online database of experimentally verified in vivo protein phosphorylation sites in the model eukaryotic organism Saccharomyces cerevisisae. This work was supported by. Canadian Institutes of Health Research grant MOP-77807 - to I. April 1, 2018 - 336 am."SEE SIMILAR BUSINESSES
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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence. With the PhosphoNET Evolution module, this website also provides information about cognate proteins in over 20 other species that may share these human phosphosites. This helps to define the most functionally important phosphosites as these are expected to be highly conserved in nature. It is possible for commercial vendors of signal transduction reagents and services.
A database for experimentally determined kinase-substrate relationships.